Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031502 | 0.86 | SLC2A1 (0.35) | SLC2A1HSD17B10CYP2D6CHEK1CDK8 | |
| SCHEMBL18268231 | 0.80 | IDO1 (0.46) | SLC2A1CYP2D6CHEK1CDK8NEK2 | |
| SCHEMBL2524191 | 0.78 | CYP2D6 (0.38) | SLC2A1CYP2D6CHEK1CDK8NEK2 | |
| SCHEMBL2782814 | 0.76 | CNR1 (0.56) | SLC2A1HSD17B10CNR1CNR2EPHX1 | |
| SCHEMBL5699450 | 0.75 | IDO1 (0.46) | SLC2A1HSD17B10CYP2D6CHEK1CDK8 | |
| SCHEMBL6335916 | 0.74 | CYP2D6 (0.44) | HSD17B10CYP2D6CHEK1CDK8NEK2 | |
| SCHEMBL3765915 | 0.73 | ANPEP (0.36) | SLC2A1HSD17B10CYP2D6KDM4EHPGD | |
| SCHEMBL8928010 | 0.73 | ANPEP (0.36) | SLC2A1HSD17B10CYP2D6KDM4EHPGD | |
| SCHEMBL6362894 | 0.73 | KDM4E (0.47) | HSD17B10EPHX1KDM4EALDH1A1KMT2A | |
| SCHEMBL5415754 | 0.72 | METAP2 (0.44) | HSD17B10CYP2D6CHEK1CDK8NEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1643958-A2 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | NST Neurosurvival Technologies Ltd. (IL) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110339-A2 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2004-12-23 | — | — | WO | disclosed |