Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765915 | 1.00 | ANPEP (0.36) | ANPEPCYP2D6METAP2METAP1HSD17B10 | |
| Sulfuric Acid SCHEMBL6255048 | 0.84 | ANPEP (0.46) | ANPEPHSD17B10ALDH1A1GAAMEN1 | |
| SCHEMBL3931602 | 0.80 | ANPEP (0.50) | ANPEPCYP2D6ALDH1A1GAAMEN1 | |
| SCHEMBL18268231 | 0.80 | IDO1 (0.46) | CYP2D6METAP2METAP1NCEH1SLC2A1 | |
| SCHEMBL2524191 | 0.78 | CYP2D6 (0.38) | CYP2D6METAP2METAP1GAASLC2A1 | |
| SCHEMBL3497623 | 0.77 | CA12 (0.45) | CYP2D6METAP2METAP1HSD17B10ALDH1A1 | |
| SCHEMBL9508266 | 0.76 | KMT2A (0.39) | CYP2D6ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8899666 | 0.76 | NCEH1 (0.36) | CYP2D6METAP2METAP1HSD17B10ALDH1A1 | |
| SCHEMBL134373 | 0.75 | CYP1A2 (0.46) | ALDH1A1CYP1A2 | |
| SCHEMBL5173798 | 0.74 | ALDH1A1 (0.54) | CYP2D6METAP2METAP1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335532-A | SARS-COV-2 quick detection test | NLC制药有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-116457099-A | Portable device and method for analyzing a sample | 生米公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-115335532-A | SARS-COV-2 quick detection test | NLC制药有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-114585750-A | Method for detecting or differentiating chikungunya virus, dengue virus and Zika virus | 新加坡科技研究局 | 2022-06-03 | — | — | CN | disclosed |
| EP-0458901-B1 | INHIBITING TRANSFORMATION OF CELLS HAVING ELEVATED PURINE METABOLIC ENZYME ACTIVITY | MASSACHUSETTS INST TECHNOLOGY (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5324731-A | Method of inhibiting transformation of cells in which purine metabolic enzyme activity is elevated | AMIRA, INC. (US) | 1994-06-28 | — | — | US | disclosed |
| EP-0557383-A1 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008456-A2 | METHOD OF INHIBITING TRANSFORMATION, GROWTH AND METASTASIS OF CELLS IN WHICH PURINE METABOLIC ENZYME ACTIVITY IS ELEVATED | AMIRA, INC. (US) | 1992-05-29 | — | — | WO | disclosed |