SCHEMBL6032492

SCHEMBL6032492

CCc1c(N2CC(=O)NC2=O)ccc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.38
MAPT P10636 5/20 0.38
MEN1 O00255 5/20 0.38
LMNA P02545 3/20 0.38
ELANE P08246 1/20 0.38
NCEH1 Q6PIU2 1/20 0.38
DDB1 Q16531 2/20 0.36
CRBN Q96SW2 2/20 0.36
SHMT2 P34897 1/20 0.36
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1878252 0.77 POLB (0.47) KMT2AMAPTMEN1LMNAELANE
SCHEMBL2191985 0.75 LMNA (0.58) KMT2AMAPTMEN1LMNADDB1
SCHEMBL10823571 0.68 CHEK1 (0.45) KMT2AMAPTMEN1LMNADDB1
SCHEMBL2006546 0.68 ALDH1A1 (0.41) KMT2AMAPTMEN1LMNADDB1
Aziridine SCHEMBL11873768 0.67 NCEH1 (0.44) MAPTNCEH1GLAGAAKDM4E
SCHEMBL103056 0.67 NCEH1 (0.50) MAPTNCEH1GLAGAAKDM4E
SCHEMBL2536247 0.66 DDB1 (0.72) KMT2AMAPTMEN1ELANEDDB1
SCHEMBL8570130 0.66 HSP90AA1 (0.47) MAPTLMNADDB1CRBNGAA
SCHEMBL1161044 0.66 ALDH1A1 (0.46) MAPTNCEH1GLAGAAKDM4E
SCHEMBL4630490 0.66 NCEH1 (0.49) MAPTNCEH1GLAGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022392-B2 In-situ polymerized matrix for isomerized optical recording article EASTMAN KODAK COMPANY (US) 2006-04-04 US disclosed
US-20050095390-A1 In-situ polymerized matrix for isomerized optical recording article EASTMAN KODAK COMPANY 2005-05-05 US disclosed
EP-0786691-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-12-29 EP disclosed
EP-0786692-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-11-17 EP disclosed
EP-0929840-B1 SILVER HALIDE LIGHT SENSITIVE EMULSION LAYER HAVING ENHANCED PHOTOGRAPHIC SENSITIVITY EASTMAN KODAK CO (US) 2004-02-18 EP disclosed
EP-0893731-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
EP-0887700-B1 Sensitizing dyes for enhanced light absorption EASTMAN KODAK CO (US) 2004-01-28 EP disclosed
EP-0893732-B1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK CO (US) 2003-01-22 EP disclosed
US-6376163-B1 N-OXYAZINIUM COMPOUND EASTMAN KODAK COMPANY 2002-04-23 US disclosed
US-6342341-B1 TRANSITION METAL ANTIFOGGING COMPOUND SUCH AS RUTHENIUM HEXACYANIDE, INCREASED PHOTOGRAPHIC SPEED WITH RELATIVELY LOW FOG EASTMAN KODAK COMPANY 2002-01-29 US disclosed
EP-0893732-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed
EP-0893731-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1999-01-27 EP disclosed
EP-0887700-A1 Sensitizing dyes for enhanced light absorption EASTMAN KODAK COMPANY (US) 1998-12-30 EP disclosed
EP-0467370-B1 Sensitizing dyes for photographic materials EASTMAN KODAK CO (US) 1998-05-13 EP disclosed
US-5747236-A FRAGMENTABLE ELECTRON DONOR EASTMAN KODAK COMPANY (US) 1998-05-05 US disclosed
EP-0786690-A2 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed
EP-0786692-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed
EP-0786691-A1 Silver halide light sensitive emulsion layer having enhanced photographic sensitivity EASTMAN KODAK COMPANY (US) 1997-07-30 EP disclosed
US-4075017-A Photothermographic material containing a combination of energy-sensitive organic dyes and process of forming a positive or negative image with the material EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-RE29168-E HEAT SENSITIVE, ANTIHALATION LAYER EASTMAN KODAK COMPANY (US) 1977-04-05 US disclosed