Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726525 | 0.92 | ROCK2 (0.66) | ROCK2 | |
| SCHEMBL2726527 | 0.92 | ROCK2 (0.66) | ROCK2 | |
| SCHEMBL6032749 | 0.88 | ROCK2 (0.63) | ROCK2 | |
| SCHEMBL6033639 | 0.88 | ROCK2 (0.61) | ROCK2 | |
| SCHEMBL6031225 | 0.87 | ROCK2 (0.47) | ROCK2 | |
| SCHEMBL6032069 | 0.87 | ROCK2 (0.46) | ROCK2 | |
| SCHEMBL2726997 | 0.86 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL2725363 | 0.85 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL2725360 | 0.85 | ROCK2 (0.58) | ROCK2 | |
| SCHEMBL6031918 | 0.84 | ROCK2 (0.53) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054367-A1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |