Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 15/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033362 | 0.79 | TGM2 (0.66) | TGM2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6033943 | 0.77 | TGM2 (0.52) | TGM2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6033985 | 0.75 | TGM2 (0.59) | TGM2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6034980 | 0.74 | TGM2 (0.65) | TGM2ALDH1A1MAPK1HSD17B10HTT | |
| SCHEMBL6034875 | 0.73 | TGM2 (0.56) | TGM2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6033952 | 0.73 | TGM2 (0.56) | TGM2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL6034054 | 0.72 | TGM2 (0.66) | TGM2HTTMAPT | |
| SCHEMBL6034873 | 0.72 | TGM2 (0.68) | TGM2MAPK1 | |
| SCHEMBL26376920 | 0.71 | TGM2 (0.80) | TGM2ALDH1A1MAPK1HSD17B10HTT | |
| SCHEMBL6034427 | 0.70 | TGM2 (0.65) | TGM2ALDH1A1ALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060702-A1 | SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-06-08 | — | — | WO | disclosed |