Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 17/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034240 | 0.86 | TGM2 (0.68) | TGM2 | |
| SCHEMBL6034054 | 0.84 | TGM2 (0.66) | TGM2 | |
| SCHEMBL6034879 | 0.81 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6037627 | 0.79 | TGM2 (0.76) | TGM2MAPK1 | |
| SCHEMBL6034346 | 0.78 | MAPK1 (0.63) | TGM2MAPK1GRM1KDM4ETSHR | |
| SCHEMBL6033982 | 0.74 | TGM2 (0.64) | TGM2MAPK1KDM4ETSHR | |
| SCHEMBL6033372 | 0.73 | TGM2 (0.60) | TGM2KDM4E | |
| SCHEMBL6033358 | 0.72 | TGM2 (0.53) | TGM2MAPK1 | |
| SCHEMBL6037620 | 0.72 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6033420 | 0.70 | TGM2 (0.70) | TGM2MAPK1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060702-A1 | SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-06-08 | — | — | WO | disclosed |