Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.79 |
| ▸ | MEN1 | O00255 | 9/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033436 | 0.92 | KMT2A (0.77) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6034353 | 0.88 | TGM2 (1.00) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6037643 | 0.87 | TGM2 (0.74) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6034026 | 0.86 | TGM2 (0.80) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6033409 | 0.84 | TGM2 (0.75) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6034350 | 0.83 | TGM2 (0.73) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6037622 | 0.79 | TGM2 (0.77) | TGM2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6034970 | 0.79 | TGM2 (1.00) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6033399 | 0.77 | TGM2 (0.77) | TGM2MEN1KMT2AMAPTKDM4E | |
| SCHEMBL6037621 | 0.76 | TGM2 (0.77) | TGM2MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634075-B1 | Electronic device for communication with living cells | YISSUM RES DEV CO (IL) | 2015-01-14 | — | — | EP | disclosed |
| US-20060183759-A1 | Tissue transglutaminase inhibitors | BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | 2006-08-17 | — | — | US | disclosed |
| WO-2006060702-A1 | SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| EP-1634075-A1 | ELECTRONIC DEVICE FOR COMMUNICATION WITH LIVING CELLS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004109282-A1 | ELECTRONIC DEVICE FOR COMMUNICATION WITH LIVING CELLS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183759-A1 | Tissue transglutaminase inhibitors | TGM2, HNMT, TPMT | TGM2 1/4885MEN1 2068/4885KMT2A 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.