Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28751648 | 0.89 | GAA (0.33) | — | |
| SCHEMBL7934861 | 0.82 | IRAK4 (0.32) | — | |
| SCHEMBL77640 | 0.82 | CA9 (0.35) | NPC1RAB9ASMN1; SMN2NFE2L2TUBB4A | |
| SCHEMBL28792612 | 0.78 | POLB (0.31) | SMN1; SMN2 | |
| SCHEMBL8775726 | 0.76 | CA1 (0.39) | KMT2A | |
| SCHEMBL9672160 | 0.74 | NFE2L2 (0.39) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28327253 | 0.73 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2NFE2L2 | |
| SCHEMBL9672899 | 0.73 | MAPK1 (0.38) | KMT2ARAB9A | |
| SCHEMBL9674315 | 0.72 | PARP10 (0.32) | — | |
| SCHEMBL9671350 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1632470-A2 | Calcium receptor active molecules | NPS PHARMACEUTICALS, INC. (US) | 2006-03-08 | — | — | EP | claimed |