SCHEMBL60337

SCHEMBL60337

O=[N+]([O-])c1ccc(I)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
HSD17B10 Q99714 2/20 0.56
ACHE P22303 1/20 0.56
LMNA P02545 1/20 0.55
CES1 P23141 1/20 0.52
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
TSHR P16473 2/20 0.50
LOXL2 Q9Y4K0 1/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA13 Q8N1Q1 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1361170 0.93 CA1 (0.55) ALDH1A1HSD17B10ACHELMNACES1
Iodobenzene SCHEMBL28041126 0.91 ALDH1A1 (0.65) ALDH1A1HSD17B10ACHELMNACES1
SCHEMBL28959698 0.89 MEN1 (0.55) ALDH1A1HSD17B10ACHELMNACES1
SCHEMBL28155214 0.89 CYP1A2 (0.56) ALDH1A1HSD17B10ACHELMNATDP1
Iodobenzene SCHEMBL27812839 0.87 ALDH1A1 (0.68) ALDH1A1HSD17B10ACHELMNACES1
SCHEMBL10410089 0.87 APP (0.64) APPMAPK1
SCHEMBL10410090 0.87 APP (0.64) APPMAPK1
SCHEMBL4629644 0.87 HSPB1 (0.50) ALDH1A1HSD17B10ACHELMNACES1
SCHEMBL14263355 0.87 POLB (0.63) ALDH1A1HSD17B10ACHECA1CA2
SCHEMBL4612005 0.87 HSPB1 (0.66) ALDH1A1LMNACES1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2226 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119528747-B Preparation method of 3,4' -diaminodiphenyl ether 烟台泰和新材高分子新材料研究院有限公司 2025-05-13 CN claimed
CN-119972147-A Calcium carbonate/carbon composite carrier supported ruthenium catalyst, preparation method and application 郑州大学 2025-05-13 CN claimed
CN-119819295-A Preparation method and application method of silver catalyst 宁夏银飞医药科技有限公司 2025-04-15 CN claimed
CN-117362311-B Foscoline tetracyclic analogue and preparation method thereof 南通大学 2025-04-04 CN claimed
CN-117586274-B Forskolin ring-expanding derivative and preparation method and application thereof 南通大学附属医院 2025-04-01 CN claimed
CN-119680569-A Preparation method and hydrogenation application of hollow IrCu/C nano-catalyst 聊城大学 2025-03-25 CN claimed
CN-119528747-A Preparation method of 3,4' -diaminodiphenyl ether 烟台泰和新材高分子新材料研究院有限公司 2025-02-28 CN claimed
CN-117362310-B Forskolin oxygen bridged ring derivative and preparation method thereof 南通大学 2024-12-06 CN claimed
CN-119069693-A Negative electrode slurry, negative electrode plate, battery monomer, battery and electric equipment 宁德时代新能源科技股份有限公司 2024-12-03 CN claimed
CN-118874537-A Catalyst, preparation method thereof and method for preparing aromatic amine compound 厦门大学 2024-11-01 CN claimed
US-5816707-A Reversible chemical thermometer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-10-06 US claimed
EP-0684463-A1 Temperature indicating device and composition for use therein PyMaH Corporation (US) 1995-11-29 EP claimed
EP-0387322-B1 ORGANIC MATERIAL FOR NON LINEAR OPTICS ALCATEL NV (NL) 1994-08-31 EP claimed
US-5155232-A ORGANIC MATERIAL FOR NON-LINEAR OPTICS ALCATEL N.V. (NL) 1992-10-13 US claimed
US-5094545-A Solid solution with nucleating agent and indicator dye PYMA CORPORATION (US) 1992-03-10 US claimed
EP-0386116-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-09-12 EP claimed
WO-1989004338-A1 PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) EASTMAN KODAK COMPANY (US) 1989-05-18 WO claimed
EP-0070198-B1 RADIATION-SENSITIVE COMPOSITION AND PATTERN-FORMATION METHOD USING THE SAME Hitachi, Ltd. (JP) 1985-06-19 EP claimed
EP-0070198-A1 Radiation-sensitive composition and pattern-formation method using the same Hitachi, Ltd. (JP) 1983-01-19 EP claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed