Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.60 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.60 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.60 |
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 5/20 | 0.51 |
| ▸ | TDP2 | O95551 | 2/20 | 0.51 |
| ▸ | HK1 | P19367 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | MITF | O75030 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440919 | 0.94 | IDO1 (0.68) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL119489 | 0.94 | IDO1 (0.68) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Formic Acid SCHEMBL29070823 | 0.84 | IDO1 (0.56) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Tert-Butanol SCHEMBL1458212 | 0.82 | IDO1 (0.54) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL21294602 | 0.81 | IDO1 (0.47) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Trifluoroacetic Acid SCHEMBL4267259 | 0.77 | IDO1 (0.47) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL1510327 | 0.77 | RAB9A (0.68) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Dichlon SCHEMBL29360991 | 0.77 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| Dichlon SCHEMBL45723 | 0.77 | IDO1 (1.00) | IDO1DNMT1DNMT3LDNMT3AS100A4 | |
| SCHEMBL29563346 | 0.77 | RAB9A (0.68) | IDO1DNMT1DNMT3LDNMT3AS100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122377-B2 | Acid-labile isotope-coded extractant (ALICE) and its use in quantitative mass spectrometric analysis of protein mixtures | GENETICS INSTITUTE, LLC (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1330654-B1 | ACID-LABILE ISOTOPE-CODED EXTRACTANT (ALICE) IN MASS SPECTOMETRIC ANALYSIS | INST GENETICS LLC (US) | 2006-03-08 | — | — | EP | disclosed |
| US-6902936-B2 | Acid-labile isotope-coded extractant (ALICE) and its use in quantitative mass spectrometric analysis of protein mixtures | GENENTICS INSTITUTE, INC. (US) | 2005-06-07 | — | — | US | disclosed |
| US-20050014278-A1 | Acid-labile isotope-coded extractant (ALICE) and its use in quantitative mass spectrometric analysis of protein mixtures | QIU YONGCHANG (US) | 2005-01-20 | — | — | US | disclosed |
| EP-1330654-A2 | ACID-LABILE ISOTOPE-CODED EXTRACTANT (ALICE) IN MASS SPECTOMETRIC ANALYSIS | Genetics Institute, LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-20020164809-A1 | Acid-labile isotope-coded extractant (ALICE) and its use in quantitative mass spectrometric analysis of protein mixtures | GENETICS INSTITUTE, INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002048717-A2 | ACID-LABILE ISOTOPE-CODED EXTRACTANT (ALICE) IN MASS SPECTROMETRIC ANALYSIS | GENETICS INSTITUTE, LLC. (US) | 2002-06-20 | — | — | WO | disclosed |