SCHEMBL6034403

SCHEMBL6034403

CNc1cn[nH]c1C(N)N

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.32
AOC1 P19801 1/20 0.32
AOC3 Q16853 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20331523 0.80 PDPK1 (0.34) PDPK1SMN1; SMN2
SCHEMBL10280973 0.68
SCHEMBL23863591 0.65 PDPK1 (0.55) PDPK1SMN1; SMN2
SCHEMBL21964550 0.64 LMNA (0.33)
SCHEMBL21964551 0.63 CDK1 (0.33)
SCHEMBL24059120 0.63 LMNA (0.51) SMN1; SMN2
SCHEMBL5707300 0.59
SCHEMBL24070506 0.59
SCHEMBL25010037 0.59 TIPARP (0.43)
SCHEMBL21863628 0.57 GLA (0.58) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1367983-A1 MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS L'OREAL (FR) 2003-12-10 EP claimed
WO-2002069922-A1 MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS L'OREAL (FR) 2002-09-12 WO claimed
EP-2903585-A2 AGENT FOR ALTERING THE COLOR OF KERATIN FIBERS COMPRISING A FATTY SUBSTANCE, A RHEOLOGY MODIFYING POLYMER, AND DIRECT DYES IN AN EMULSION SYSTEM L'OREAL (FR) 2015-08-12 EP disclosed
EP-2903584-A2 AGENT FOR ALTERING THE COLOR OF KERATIN FIBERS CONTAINING A FATTY SUBSTANCE AND A RHEOLOGY MODIFYING POLYMER IN AN EMULSION SYSTEM L'OREAL (FR) 2015-08-12 EP disclosed
WO-2014053504-A2 AGENT FOR ALTERING THE COLOR OF KERATIN FIBERS CONTAINING A FATTY SUBSTANCE AND A RHEOLOGY MODIFYING POLYMER IN AN EMULSION SYSTEM L'OREAL (FR) 2014-04-10 WO disclosed
WO-2014053503-A2 AGENT FOR ALTERING THE COLOR OF KERATIN FIBERS COMPRISING A FATTY SUBSTANCE, A RHEOLOGY MODIFYING POLYMER, AND DIRECT DYES IN AN EMULSION SYSTEM L'OREAL (FR) 2014-04-10 WO disclosed
EP-1651181-A1 DYEING COMPOSITION COMPRISING AT LEAST ONE DYE PRECURSOR AND ONE AMPHIPHILIC BLOCK COPOLYMER L'OREAL (FR) 2006-05-03 EP disclosed
WO-2005014591-A1 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2005-02-17 WO disclosed
WO-2004103327-A1 DYEING COMPOSITION COMPRISING AT LEAST ONE DYE PRECURSOR AND ONE AMPHIPHILIC BLOCK COPOLYMER L'OREAL (FR) 2004-12-02 WO disclosed