Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034543 | 1.00 | TSHR (0.52) | TSHRALDH1A1CYP3A4CA2MAPK1 | |
| SCHEMBL28817970 | 0.86 | LCK (0.52) | FAAHLCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL25342792 | 0.85 | MME (0.41) | ALDH1A1CA2MAPK1TDP1FAAH | |
| SCHEMBL25241027 | 0.83 | CA2 (0.51) | TSHRALDH1A1CYP3A4CA2HTT | |
| Hydrochloric Acid SCHEMBL30731552 | 0.83 | MME (0.40) | ALDH1A1CA2MAPK1FAAHSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28550969 | 0.83 | MME (0.40) | ALDH1A1CA2MAPK1FAAHSMN1; SMN2 | |
| SCHEMBL18155539 | 0.79 | TSHR (0.48) | TSHRALDH1A1CYP3A4CA2MAPK1 | |
| SCHEMBL17363803 | 0.78 | TSHR (0.47) | TSHRALDH1A1CYP3A4CA2MAPK1 | |
| SCHEMBL5468966 | 0.78 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4CA2MAPK1 | |
| SCHEMBL4162585 | 0.77 | TSHR (0.59) | TSHRALDH1A1CYP3A4CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060008887-A1 | Production of carboxylic acid and carbonic acid derivatives using a thermostable esterase | GOLDSCHMIDT AG (DE) | 2006-01-12 | — | — | US | disclosed |