1,4-Butanediol

1,4-Butanediol

SCHEMBL6034635

CCC(CO)(CO)CO.OCCCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
LMNA P02545 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CYP4F2 P78329 2/20 0.35
CYP4A11 Q02928 2/20 0.35
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28113712 0.97 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
1,5-Pentanediol SCHEMBL484472 0.97 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
1,6-Hexanediol SCHEMBL2733820 0.97 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
SCHEMBL6673802 0.97 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
1,6-Hexanediol SCHEMBL10441623 0.94 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
SCHEMBL21409482 0.91 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
Octanol SCHEMBL28203059 0.89 LMNA (0.65) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
Dodecanol SCHEMBL27628573 0.89 LMNA (0.65) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
Butyl Alcohol SCHEMBL25381663 0.88 ALDH1A1 (0.61) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10
SCHEMBL435370 0.88 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TSHRLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297252-B1 Crosslinked polyetherurethane membranes useful in blood electrolyte sensors BECTON DICKINSON CO (US) 1994-02-16 EP claimed
CN-112987496-B Photosensitive resin composition and transfer film using same 旭化成株式会社 2024-06-14 CN disclosed
WO-2023074676-A1 POLYOL COMPOSITION FOR POLYURETHANE FOAM 東ソー株式会社 2023-05-04 WO disclosed
EP-4165104-A1 PROCESS FOR PRODUCING POLYOXYMETHYLENE-POLYOXYALKYLENE COPOLYMERS Covestro Deutschland AG (DE) 2023-04-19 EP disclosed
EP-4127021-A1 METHOD FOR PRODUCING AN ETHER ESTEROL Covestro Deutschland AG (DE) 2023-02-08 EP disclosed
EP-3898759-A1 PROCESS FOR PREPARING A POLYESTER USING A 4-MEMBERED RING LACTONE Covestro Intellectual Property GmbH & Co. KG (DE) 2021-10-27 EP disclosed
CN-112987496-A Photosensitive resin composition and transfer film using the same 旭化成株式会社 2021-06-18 CN disclosed
WO-2020127008-A1 PROCESS FOR PREPARING A POLYESTER USING A 4-MEMBERED RING LACTONE COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2020-06-25 WO disclosed
US-20160195188-A1 NITRILE RUBBER-METAL LAMINATED GASKET MATERIAL NOK CORPORATION (JP) 2016-07-07 US disclosed
EP-3031952-A1 (NITRILE RUBBER)-METAL-LAMINATED GASKET MATERIAL Nok Corporation (JP) 2016-06-15 EP disclosed
CN-105637119-A (NITRILE RUBBER)-METAL-LAMINATED GASKET MATERIAL NOK CORP 2016-06-01 CN disclosed
US-7153926-B2 Golf ball and process for producing the same SRI SPORTS LIMITED (JP) 2006-12-26 US disclosed
US-20050079351-A1 Golf ball and process for producing the same SRI SPORTS LIMITED (JP) 2005-04-14 US disclosed
EP-0299148-B1 Polyurethane resins in water dilutable basecoats having low flash and quick-drying characteristics BASF CORP (US) 1994-07-20 EP disclosed
US-4960622-A HIGH DENSITY, FLEXIBLE POLYURETHANE, RUBBER MOLD FUTURA COATINGS, INC. (US) 1990-10-02 US disclosed
US-4940558-A COATING A ROCK WITH A FLEXIBLE RUBBER TO FORM A MOLD, FILLING THE MOLD WITH A POLYMERIZABLE MIXTURE FUTURA COATINGS, INC. (US) 1990-07-10 US disclosed
EP-0299148-A2 Polyurethane resins in water dilutable basecoats having low flash and quick-drying characteristics BASF Corporation (US) 1989-01-18 EP disclosed
US-4153777-A Polyurethane and method of making GOODYEAR AEROSPACE CORPORATION (US) 1979-05-08 US disclosed
US-3954825-A FROM A POLYAMINE AND A POLYISOCYANATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-04 US disclosed