SCHEMBL6034705

SCHEMBL6034705

N#[N+]c1cccc(Cl)c1Cl

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
PNMT P11086 2/20 0.39
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 2/20 0.38
LMNA P02545 2/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
NFKB1 P19838 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
IDO1 P14902 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GLA P06280 1/20 0.34
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
DRD2 P14416 2/20 0.31
DRD3 P35462 2/20 0.31
ADRB1 P08588 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9661562 0.98 TSHR (0.41) TSHRPNMTCYP1A2CYP2A6LMNA
Hydrochloric Acid SCHEMBL10982383 0.95 TSHR (0.39) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL2778262 0.91 TSHR (0.37) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL4661697 0.79
Hydrochloric Acid SCHEMBL4996670 0.77 TSHR (0.45) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL8776844 0.77 CYP3A4 (0.40) CYP2A6CYP3A4TDP1
Fluoride Ion SCHEMBL11775432 0.77 TSHR (0.45) TSHRPNMTCYP1A2CYP2A6LMNA
Hydrochloric Acid SCHEMBL30362972 0.77 TSHR (0.45) TSHRPNMTCYP1A2CYP2A6LMNA
SCHEMBL2565270 0.76 ALDH1A1 (0.46) TSHRCYP1A2CYP2A6LMNACYP3A4
SCHEMBL377007 0.75 TSHR (0.42) TSHRPNMTCYP1A2CYP2A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086168-A MONOAZO PIGMENTS DERIVED FROM DIAZOTIZED DI- OR TRICHLOROANILINES, PREPARATION THEREOF AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-04 US claimed
CN-115850123-B Preparation method of 2, 4-dichloroaniline/hydrazine 山东潍坊润丰化工股份有限公司 2024-04-19 CN disclosed
US-20230225911-A1 ABSORBENT ARTICLE HAVING REAGENTS FOR DETECTING MEDICAL CONDITIONS BABY RX LLC 2023-07-20 US disclosed
CN-115850123-A Preparation method of 2, 4-dichloroaniline/hydrazine 山东潍坊润丰化工股份有限公司 2023-03-28 CN disclosed
US-7105128-B2 Comprises water-impermeable support, water-permeable layer and spreading layer having function of spreading liquid uniformly, wherein water-soluble indicator for colorimetry is incorporated into spreading layer FUJI PHOTO FILM CO., LTD. (JP) 2006-09-12 US disclosed
US-20060179505-A1 Transgenic mice containing channel activating protease 1 (CAP1) gene disruptions DELTAGEN, INC. 2006-08-10 US disclosed
US-20030138352-A1 Dry analytical element using water-soluble indicator for colorimetry TANAKA HIDEAKI (JP) 2003-07-24 US disclosed
US-20020071784-A1 Dry analytical element and it's manufacturing method FUJI PHOTO FILM CO., LTD. 2002-06-13 US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed
CN-1080279-A 2, the preparation of 4-toluene dichloride SHENYANG CHEMICAL INST MINISTR (CN) 1994-01-05 CN disclosed
EP-0489085-A4 RIGID-ROD POLYMERS MAXDEM INC (US) 1992-08-05 EP disclosed
EP-0489085-A1 RIGID-ROD POLYMERS MAXDEM INCORPORATED (US) 1992-06-10 EP disclosed
US-5086168-A MONOAZO PIGMENTS DERIVED FROM DIAZOTIZED DI- OR TRICHLOROANILINES, PREPARATION THEREOF AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0175330-B1 INTEGRAL MULTILAYER ANALYTICAL ELEMENT FOR QUANTITATIVE ANALYSIS OF BILIRUBIN FUJI PHOTO FILM CO., LTD. (JP) 1991-11-27 EP disclosed
EP-0175330-A2 Integral multilayer analytical element for quantitative analysis of bilirubin FUJI PHOTO FILM CO., LTD. (JP) 1986-03-26 EP disclosed
US-4382062-A DIAZONIUM AND PHOSPHONIUM SALTS BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1983-05-03 US disclosed