Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | GCG | P01275 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036044 | 0.96 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035777 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6255982 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035137 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035388 | 0.84 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6034684 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035813 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035895 | 0.82 | KDM4E (0.43) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035939 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EHPGDNPC1MAPT | |
| SCHEMBL6035924 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EHPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-07-06 | — | — | US | disclosed |
| EP-1358143-B1 | PROCESS AND INTERMEDIATE COMPOUNDS FOR THE PREPARATION OF PESTICIDAL FLUOROOLEFIN COMPOUNDS | BASF AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| US-6770788-B2 | REACTING A SUBSTITUTED 1-BROMO-1-FLUORO-3-ARYL-1-PROPENE AN ARYLMETHYL ZINC COMPOUND IN THE PRESENCE OF A PALLADIUM CATALYST AND A SOLVENT | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20030135075-A1 | Process and intermediate compounds for preparation of pesticidal fluoroolefin compounds | WOOD WILLIAM WAKEFIELD (US) | 2003-07-17 | — | — | US | disclosed |
| US-6495728-B2 | ARALKYLATION OF A FLUOROBROMOOLEFIN WITH AN ARALKYLZINC BROMIDE OR BIS(ARALKYL)ZINC IN PRESENCE OF A PALLADIUM CATALYST; PREPARATION OF THE OLEFIN FROM AN ALDEHYDE AND CBR3F, A PHOSPHINE OR PHOSPHORAMIDE AND ZINC | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |
| US-20020062049-A1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | BASF AKTIENGESELLSCHAFT | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135075-A1 | Process and intermediate compounds for preparation of pesticidal fluoroolefin compounds | DDT, AHR, CYP2F1 | SMN1; SMN2 2937/4885KDM4E 1766/4885HPGD 3557/4885 |
| US-20020062049-A1 | Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds | DDT, PFAS, CYP2F1 | SMN1; SMN2 3333/4885KDM4E 1506/4885HPGD 3216/4885 |
| US-20060148858-A1 | 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity | GPR119, SLC5A1, CYP4B1 | SMN1; SMN2 4408/4885KDM4E 509/4885HPGD 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.