Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 19/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6033954 | 0.89 | TGM2 (0.69) | TGM2 | |
| SCHEMBL6034975 | 0.83 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6033951 | 0.81 | TGM2 (0.77) | TGM2MEN1KMT2A | |
| SCHEMBL6034368 | 0.76 | TGM2 (0.66) | TGM2 | |
| SCHEMBL6033978 | 0.75 | TGM2 (0.48) | TGM2MEN1KMT2A | |
| SCHEMBL6033400 | 0.74 | TGM2 (0.69) | TGM2MEN1KMT2A | |
| SCHEMBL6034967 | 0.74 | TGM2 (0.70) | TGM2MEN1KMT2A | |
| SCHEMBL6034013 | 0.72 | TGM2 (1.00) | TGM2 | |
| SCHEMBL6034350 | 0.71 | TGM2 (0.73) | TGM2MEN1KMT2A | |
| SCHEMBL6033956 | 0.70 | TGM2 (1.00) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060702-A1 | SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-06-08 | — | — | WO | disclosed |