SCHEMBL6034368

SCHEMBL6034368

CC(=O)N(N)Sc1nc2scc(-c3cccc(F)c3)c2c(=O)n1-c1cccc(F)c1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6034054 0.86 TGM2 (0.66) TGM2
SCHEMBL6034980 0.80 TGM2 (0.65) TGM2
SCHEMBL6033978 0.80 TGM2 (0.48) TGM2
SCHEMBL6034372 0.80 TGM2 (1.00) TGM2
SCHEMBL6034873 0.79 TGM2 (0.68) TGM2
SCHEMBL6033382 0.78 TGM2 (0.73) TGM2
SCHEMBL6033954 0.77 TGM2 (0.69) TGM2
SCHEMBL6034920 0.77 TGM2 (0.60) TGM2
SCHEMBL6034427 0.76 TGM2 (0.65) TGM2
SCHEMBL6033982 0.76 TGM2 (0.64) TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006060702-A1 SUBSTITUED 3,4-DIHYDROTHIENO [2,3-D] PYRMIDINES AS TISSUE TRANSGLUTAMINASE INHIBITORS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2006-06-08 WO disclosed