SCHEMBL6035218

SCHEMBL6035218

FCC(F)(F)N=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL363478 0.71
SCHEMBL22265274 0.67
SCHEMBL31563734 0.58 ALDH1A1 (0.33)
SCHEMBL28999727 0.58
SCHEMBL3949055 0.58
SCHEMBL25244463 0.55 TRPA1 (0.35)
SCHEMBL4668501 0.55
SCHEMBL8764127 0.55 ALDH1A1 (0.32)
SCHEMBL17289572 0.54
SCHEMBL330601 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004182-B Preparation method of trifluoro-isothiocyanato ethane 顺毅股份有限公司 2024-01-12 CN claimed
US-12517133-B2 Macromolecule analysis employing nucleic acid encoding DF PEPTIDE ACQUISITION LLC 2026-01-06 US disclosed
US-12498378-B2 Methods for spatial analysis of proteins and related kits DF PEPTIDE ACQUISITION LLC 2025-12-16 US disclosed
US-12474346-B2 Methods and kits for multicycle encoding assay DF PEPTIDE ACQUISITION LLC 2025-11-18 US disclosed
US-12467049-B2 Methods and kits using nucleic acid encoding and/or label DF PEPTIDE ACQUISITION LLC 2025-11-11 US disclosed
US-20250237660-A1 METHODS AND KITS FOR MULTICYCLE ENCODING ASSAY Encodia, Inc. (US) 2025-07-24 US disclosed
US-12320813-B2 Macromolecule analysis employing nucleic acid encoding Encodia, Inc. (US) 2025-06-03 US disclosed
US-20250164499-A1 MACROMOLECULE ANALYSIS EMPLOYING NUCLEIC ACID ENCODING DF PEPTIDE ACQUISITION LLC 2025-05-22 US disclosed
EP-3704249-B1 KITS FOR ANALYSIS USING NUCLEIC ACID ENCODING AND/OR LABEL ENCODIA INC (US) 2025-05-21 EP disclosed
US-12292446-B2 Kits for analysis using nucleic acid encoding and/or label Encodia, Inc. (US) 2025-05-06 US disclosed
US-7115229-B2 Apparatus and method for monitoring molecular species within a medium ALPHA MOS (FR) 2006-10-03 US disclosed
US-7097973-B1 Method for monitoring molecular species within a medium ALPHA MOS (FR) 2006-08-29 US disclosed
US-20020094531-A1 Apparatus and method for monitoring molecular species within a medium ZENHAUSERN FREDERIC (US) 2002-07-18 US disclosed
US-5824556-A FORMING A DITHIOCARBAMYL-PEPTIDE, CLEAVAGING WITH ACID, ANALYZING BY MASS SPECTROMETRY TARR GEORGE E (US) 1998-10-20 US disclosed
US-4762932-A Haloguanidine intermediates IMPERIAL CHEMICAL INDUSTRIES, LTD. (GB) 1988-08-09 US disclosed
US-4604465-A Haloguanidine intermediates ICI AMERICAS, INC. (US) 1986-08-05 US disclosed
EP-0030092-B1 GUANIDINE DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-06 EP disclosed
EP-0103390-A2 Guanidine-containing esters as histamine H2 receptor blockers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-03-21 EP disclosed
US-4362728-A Haloguanidine compounds, pharmaceutical compositions and methods of use ICI AMERICAS INC. (US) 1982-12-07 US disclosed
EP-0030092-A1 Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-06-10 EP disclosed