SCHEMBL6035256

SCHEMBL6035256

O=S(=O)=C1CC=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
IDO1 P14902 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
BCHE P06276 1/20 0.36
POLB P06746 1/20 0.36
PTPRC P08575 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
PKM P14618 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
PTPN1 P18031 1/20 0.36
ACHE P22303 1/20 0.36
CES1 P23141 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
PTPN22 Q9Y2R2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiazolidinedione SCHEMBL9784317 0.81 MGAM (0.42) ALDH1A1LMNAHPGDALOX15HTT
SCHEMBL9178395 0.79
SCHEMBL29385734 0.72 CES1 (0.45) ALDH1A1IDO1HSD17B10KDM4EMEN1
SCHEMBL249997 0.72 CES1 (0.45) ALDH1A1IDO1HSD17B10KDM4EMEN1
SCHEMBL7214854 0.72 ALDH1A1 (0.38) ALDH1A1IDO1HSD17B10KDM4EMEN1
Hydrochloric Acid SCHEMBL2710070 0.71 MEN1 (0.43) ALDH1A1IDO1HSD17B10KDM4EMEN1
SCHEMBL6487919 0.71 CES1 (0.43) ALDH1A1IDO1HSD17B10KDM4EMEN1
SCHEMBL30862184 0.71 CES1 (0.43) ALDH1A1IDO1HSD17B10KDM4EMEN1
SCHEMBL30676949 0.71 CES1 (0.43) ALDH1A1IDO1HSD17B10KDM4EMEN1
Water SCHEMBL27749315 0.71 CES1 (0.43) ALDH1A1IDO1HSD17B10KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7134466-B2 Crosslinked rubber particles modified by amino(meth)acrylate groups BAYER AKTIENGESELLSCHAFT (DE) 2006-11-14 US disclosed
US-20040166317-A1 Crosslinked rubber particles modified by amino(meth)acrylate groups ARLANXEO DEUTSCHLAND GMBH (DE) 2004-08-26 US disclosed
US-5068342-A Hypoglycemic agents and antidiabetic agents AMERICAN HOME PRODUCTS CORPORATION (US) 1991-11-26 US disclosed
US-4997948-A Hypoglycemic agents AMERICAN HOME PRODUCTS (US) 1991-03-05 US disclosed