Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817349 | 1.00 | TSHR (0.57) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL29037388 | 0.83 | TSHR (0.61) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL10546690 | 0.82 | TSHR (0.59) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL6748613 | 0.82 | TSHR (0.59) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| Benzoic Acid SCHEMBL6269463 | 0.81 | TSHR (0.64) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL5194137 | 0.80 | TSHR (0.57) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL4493990 | 0.79 | PLOD2 (0.54) | KMT2AMEN1TDP1KDM4ECYP3A4 | |
| SCHEMBL1606582 | 0.79 | TSHR (0.65) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL11455228 | 0.78 | TSHR (0.59) | TSHRKMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL8938798 | 0.77 | TSHR (0.58) | TSHRKMT2AMAPTMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154889-A1 | Polyfluorinated nucleoside analogs and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154889-A1 | Polyfluorinated nucleoside analogs and methods of use thereof | POLRMT, PCNA, POLL | TSHR 3037/4885KMT2A 2886/4885MAPT 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.