Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM10 | O14672 | 7/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036220 | 0.87 | MEN1 (0.50) | MMP2MMP13MAPTALDH1A1HPGD | |
| SCHEMBL5671661 | 0.77 | ADAM10 (0.70) | ADAM10MMP2MMP1MMP3MMP13 | |
| SCHEMBL5671035 | 0.76 | ADAM10 (0.47) | ADAM10MMP2MMP1MMP3MMP13 | |
| SCHEMBL5670609 | 0.76 | ADAM10 (0.46) | ADAM10MMP2MMP1MMP3MMP13 | |
| SCHEMBL5670613 | 0.76 | ADAM10 (0.46) | ADAM10MMP2MMP1MMP3MMP13 | |
| SCHEMBL5669557 | 0.75 | ADAM10 (0.44) | ADAM10MMP2MMP1MMP3MMP13 | |
| SCHEMBL5273826 | 0.74 | ADAM10 (0.71) | ADAM10MMP2MMP1MMP3 | |
| SCHEMBL6036711 | 0.70 | NPSR1 (0.43) | ADAM10MMP2MMP1MAPTALDH1A1 | |
| SCHEMBL7205516 | 0.69 | ADAM10 (0.51) | ADAM10MMP2MMP1MMP13DRD4 | |
| SCHEMBL27900121 | 0.69 | TRPV1 (0.55) | ALDH1A1DRD4HSD11B1TRPV1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648868-B1 | HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS | CELLTECH R&D LTD (GB) | 2006-11-15 | — | — | EP | claimed |