Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 5/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669557 | 0.70 | ADAM10 (0.44) | NPSR1PKMMAPTALDH1A1HPGD | |
| SCHEMBL6036259 | 0.70 | ADAM10 (0.51) | NPSR1MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL5670609 | 0.68 | ADAM10 (0.46) | NPSR1MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL5670613 | 0.68 | ADAM10 (0.46) | NPSR1MAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL6036246 | 0.68 | ADAM10 (0.43) | PKMCYP2C19ADAM10MMP2 | |
| SCHEMBL3436367 | 0.67 | TRPV1 (0.54) | ALDH1A1 | |
| SCHEMBL3436370 | 0.67 | DRD4 (0.59) | — | |
| SCHEMBL27900121 | 0.66 | TRPV1 (0.55) | ALDH1A1CYP2C19 | |
| SCHEMBL5671661 | 0.65 | ADAM10 (0.70) | ADAM10MMP2MMP1 | |
| SCHEMBL13450177 | 0.65 | MEN1 (0.67) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648868-A1 | HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS | Celltech R & D Limited (GB) | 2006-04-26 | — | — | EP | claimed |
| WO-2004113298-A1 | HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS | CELLTECH R & D LIMITED (GB) | 2004-12-29 | — | — | WO | claimed |