SCHEMBL6036746

SCHEMBL6036746

C=C(C)C(=O)OCCCC=C(O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
THRB P10828 1/20 0.49
POLB P06746 1/20 0.43
APEX1 P27695 1/20 0.43
HTT P42858 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 4/20 0.35
HPGD P15428 1/20 0.31
EP300 Q09472 1/20 0.31
ALOX15 P16050 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26685101 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
Ammonia Solution, Strong SCHEMBL28030632 0.82 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL30854793 0.81 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20745132 0.81 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL29216883 0.80 TSHR (0.57) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23754643 0.80 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28695108 0.79 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL11120335 0.79 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL28574150 0.79 TSHR (0.70) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28322142 0.79 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1209492-B1 Formation of materials such as waveguides with a refractive index step NAT UNIV IRELAND CORK (IE) 2004-02-04 EP claimed
EP-1633805-A1 METHOD FOR PRODUCING SCRATCH-RESISTANT COATING SYSTEMS DEVOID OF CONDENSATION Bayer MaterialScience AG (DE) 2006-03-15 EP disclosed
EP-1565768-A1 LAMINATED SYSTEM, COATING COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF Bayer MaterialScience AG (DE) 2005-08-24 EP disclosed
EP-1549701-A1 METHOD FOR PRODUCING A SCRATCH-RESISTANT LAYER SYSTEM Bayer MaterialScience AG (DE) 2005-07-06 EP disclosed
EP-1549700-A1 LAYER SYSTEM AND METHOD FOR PRODUCING THE SAME Bayer MaterialScience AG (DE) 2005-07-06 EP disclosed
WO-2004108801-A1 METHOD FOR PRODUCING SCRATCH-RESISTANT COATING SYSTEMS DEVOID OF CONDENSATION BAYER MATERIALSCIENCE AG (DE) 2004-12-16 WO disclosed
WO-2004044627-A1 LAMINATED SYSTEM, COATING COMPOSITION AND METHOD FOR THE PRODUCTION THEREOF BAYER MATERIALSCIENCE AG (DE) 2004-05-27 WO disclosed
WO-2004031273-A1 LAYER SYSTEM AND METHOD FOR PRODUCING THE SAME BAYER MATERIALSCIENCE AG (DE) 2004-04-15 WO disclosed
WO-2004031272-A1 METHOD FOR PRODUCING A SCRATCH-RESISTANT LAYER SYSTEM BAYER MATERIALSCIENCE AG (DE) 2004-04-15 WO disclosed
US-6696143-B1 ULTRAVIOLET CURABLE ORGANOSILICON POLYMER AND COLLOIDAL SILICA LA POINT DAVID A (US) 2004-02-24 US disclosed
EP-0424006-B1 Silane free radiation curable abrasion resistant coatings DOW CORNING (US) 1995-12-20 EP disclosed
US-5188900-A Substrates having an abrasion-resistant coating formed thereon DOW CORNING CORPORATION (US) 1993-02-23 US disclosed
US-5126394-A Silane-free DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
EP-0439294-A1 Alkoxy-functional silane compositions for unprimed adhesion to polycarbonate DOW CORNING CORPORATION (US) 1991-07-31 EP disclosed
EP-0439293-A1 Alkoxy-functional silane compositions for unprimed adhesion to polycarbonate DOW CORNING CORPORATION (US) 1991-07-31 EP disclosed
EP-0424006-A2 Silane free radiation curable abrasion resistant coatings DOW CORNING CORPORATION (US) 1991-04-24 EP disclosed
EP-0055726-A4 ABRASION RESISTANT ULTRAVIOLET LIGHT CURABLE HARD COATING COMPOSITIONS. GEN ELECTRIC (US) 1982-11-25 EP disclosed
US-4348462-A Abrasion resistant ultraviolet light curable hard coating compositions GENERAL ELECTRIC COMPANY (US) 1982-09-07 US disclosed
EP-0055726-A1 ABRASION RESISTANT ULTRAVIOLET LIGHT CURABLE HARD COATING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1982-07-14 EP disclosed
WO-1982000295-A1 ABRASION RESISTANT ULTRAVIOLET LIGHT CURABLE HARD COATING COMPOSITIONS GEN ELECTRIC (US) 1982-02-04 WO disclosed