Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322142 | 0.93 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2672823 | 0.84 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL23754643 | 0.82 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26685101 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6036746 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28695108 | 0.82 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5248589 | 0.81 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1949649 | 0.81 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5366050 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27892885 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017473-A | Zwitterionic copolymer, preparation method and application | CHINA PETROLEUM & CHEMICAL | 2015-11-04 | — | — | CN | disclosed |