Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 4/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888641 | 1.00 | CYP19A1 (0.36) | CYP19A1ARCYP3A4USP2NR3C1 | |
| SCHEMBL3466312 | 1.00 | CYP19A1 (0.36) | CYP19A1ARCYP3A4USP2NR3C1 | |
| SCHEMBL6676011 | 0.88 | LMNA (0.45) | CYP19A1ARCYP3A4USP2NR3C1 | |
| SCHEMBL5814451 | 0.86 | CYP19A1 (0.42) | CYP19A1ARCYP3A4USP2NR3C1 | |
| SCHEMBL5681321 | 0.85 | CYP3A4 (0.37) | ARCYP3A4USP2NR3C1PGR | |
| SCHEMBL4225856 | 0.83 | CYP19A1 (0.41) | CYP19A1ARCYP3A4USP2NR3C1 | |
| SCHEMBL8661015 | 0.81 | LMNA (0.44) | CYP19A1CYP3A4USP2NR3C1PGR | |
| SCHEMBL6521590 | 0.81 | LMNA (0.44) | CYP19A1CYP3A4USP2NR3C1PGR | |
| SCHEMBL1847854 | 0.81 | LMNA (0.44) | CYP19A1CYP3A4USP2NR3C1PGR | |
| SCHEMBL6425507 | 0.79 | AR (0.46) | CYP19A1ARCYP3A4USP2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680163-A1 | DRY POWDER INHALER | Astrazeneca AB (SE) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005035036-A1 | DRY POWDER INHALER | ASTRAZENECA AB (SE) | 2005-04-21 | — | — | WO | disclosed |