SCHEMBL5814451

SCHEMBL5814451

CCC(=O)O[C@]1(C(=O)O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C(O)=C[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 15/20 0.42
AR P10275 1/20 0.42
CYP3A4 P08684 3/20 0.38
LMNA P02545 2/20 0.38
USP2 O75604 2/20 0.38
MLNR O43193 1/20 0.38
NR1I2 O75469 1/20 0.38
ABCB11 O95342 1/20 0.38
NR3C1 P04150 1/20 0.38
PGR P06401 1/20 0.38
MAPT P10636 1/20 0.38
CYP3A5 P20815 1/20 0.38
PPARG P37231 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4225856 0.93 CYP19A1 (0.41) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL6888641 0.86 CYP19A1 (0.36) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL6036866 0.86 CYP19A1 (0.36) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL3466312 0.86 CYP19A1 (0.36) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL8587966 0.86 LMNA (0.54) CYP19A1CYP3A4LMNAUSP2MLNR
SCHEMBL10823646 0.82 PGR (0.41) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL2401799 0.81 CYP19A1 (0.37) CYP19A1ARCYP3A4LMNANR1I2
SCHEMBL11500447 0.80 AR (0.54) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL18662883 0.79 LMNA (0.52) CYP19A1ARCYP3A4LMNAUSP2
SCHEMBL4561313 0.78 CYP19A1 (0.35) CYP19A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006011148-A2 NOVEL CRYSTALLINE FORMS OF 6ALPHA, 9ALPHA-DIFLUORO-11BETA HYDROXY-16ALPHA-METHYL-3-OXO-17ALPHA-PROPIONYLOXY-ANDROSTA-1,4-DIENE-17BETA-CARBOXYLIC ACID AND PROCESSES FOR PREPARATION THEREOF CHEMAGIS LTD. (IL) 2006-02-02 WO disclosed