Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112338 | 0.89 | TRPV1 (0.59) | HDAC2HDAC8CYP3A4HIF1AESR1 | |
| SCHEMBL8627426 | 0.87 | TRPV1 (0.54) | HDAC2HDAC8HDAC1 | |
| SCHEMBL17967143 | 0.82 | HDAC1 (0.57) | HDAC2HDAC8CYP3A4CYP2C19HIF1A | |
| SCHEMBL2836138 | 0.82 | CYP3A4 (0.53) | CYP3A4CYP2C19HIF1ACYP1A2CYP2D6 | |
| SCHEMBL8532525 | 0.82 | CYP1A2 (0.51) | HDAC2HDAC8CYP3A4CYP2C19HIF1A | |
| SCHEMBL27606163 | 0.82 | LMNA (0.53) | CYP3A4CYP2C19HIF1ACYP1A2CYP2D6 | |
| SCHEMBL967387 | 0.82 | HDAC2 (0.68) | HDAC2HDAC8CYP3A4CYP2C19HIF1A | |
| SCHEMBL8238392 | 0.82 | HDAC8 (0.89) | HDAC2HDAC8ESR1ESR2HDAC1 | |
| SCHEMBL15092830 | 0.81 | HDAC2 (0.50) | HDAC2HDAC8CYP3A4CYP2C19HIF1A | |
| SCHEMBL4409663 | 0.81 | FFAR1 (0.56) | HDAC2HDAC8CYP3A4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121698775-A | 1- {2- [3- (4-Hydroxyphenyl) propionyl ] diazinon } behene-1-one, application and preparation method | 湖南鼎一致远科技发展股份有限公司 | 2026-03-20 | — | — | CN | disclosed |
| CN-118541011-A | Polymer material for piezoelectric device | 株式会社大阪曹达 | 2024-08-23 | — | — | CN | disclosed |
| EP-3762441-A1 | POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-01-13 | — | — | EP | disclosed |
| US-20200399466-A1 | POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2020-12-24 | — | — | US | disclosed |
| CN-111936542-A | Polyurethane foams based on polyether carbonate polyols | 科思创知识产权两合公司 | 2020-11-13 | — | — | CN | disclosed |
| WO-2019170590-A1 | POLYURETHANE FOAMS BASED ON POLYETHERCARBONATE POLYOLS | COVESTRO DEUTSCHLAND AG (DE) | 2019-09-12 | — | — | WO | disclosed |
| EP-3068443-B1 | RESIDUALIZING LINKERS AND USES THEREOF | CENTRE FOR PROBE DEV AND COMMERCIALIZATION (CA) | 2019-04-10 | — | — | EP | disclosed |
| CN-108699428-A | Refrigerant mixtures comprising difluoromethane, pentafluoroethane, tetrafluoroethane, tetrafluoropropene and carbon dioxide and uses thereof | 科慕埃弗西有限公司 | 2018-10-23 | — | — | CN | disclosed |
| EP-2760856-B1 | SELECTIVE NR2B ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2016-09-14 | — | — | EP | disclosed |
| US-8722670-B2 | Selective NR2B antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-13 | — | — | US | disclosed |
| US-20130085138-A1 | Selective NR2B Antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-20060035279-A1 | Anti-GPE antibodies, their uses and assays for weakly immunogenic molecules | NEUREN PHARMACEUTICALS LTD. (NZ) | 2006-02-16 | — | — | US | disclosed |
| EP-1414804-A1 | ACYLSEMICARBAZIDES AND THEIR USE AS CYCLIN DEPENDENT KINASE (CDK) INHIBITORS | Bristol-Myers Squibb Pharma Company (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2002034721-A1 | ACYLSEMICARBAZIDES AND THEIR USE AS CYCLIN DEPENDENT KINASE (CDK) INHIBITORS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-05-02 | — | — | WO | disclosed |
| US-6291504-B1 | POTENT INHIBITORS OF THE CLASS OF ENZYMES KNOWN AS CYCLIN DEPENDENT KINASES | DUPONT PHARMACEUTICALS COMPANY | 2001-09-18 | — | — | US | disclosed |
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0721146-A2 | Hydrazide redox-dye-releasing compounds for photothermographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| US-5492803-A | Hydrazide redox-dye-releasing compounds for photothermographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085138-A1 | Selective NR2B Antagonists | GRIN2B, GRIN2A, GRIN3A | HDAC2 865/4885HDAC8 1047/4885CYP3A4 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.