SCHEMBL8627426

SCHEMBL8627426

NNC(=O)CCCCc1ccc(O)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.54
HDAC2 Q92769 5/20 0.51
HDAC1 Q13547 4/20 0.51
HDAC8 Q9BY41 2/20 0.51
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
HDAC9 Q9UKV0 1/20 0.51
HDAC5 Q9UQL6 1/20 0.51
ACHE P22303 2/20 0.51
SGMS1 Q86VZ5 2/20 0.51
SGMS2 Q8NHU3 2/20 0.51
DPP4 P27487 1/20 0.50
ALOX5 P09917 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4112338 0.95 TRPV1 (0.59) TRPV1HDAC2HDAC1HDAC8HDAC3
SCHEMBL6037022 0.87 HDAC2 (0.62) HDAC2HDAC1HDAC8
SCHEMBL31064053 0.84 HDAC1 (0.50) HDAC2HDAC1HDAC8HDAC3HDAC4
SCHEMBL8113734 0.84 HDAC1 (0.69) HDAC2HDAC1HDAC8HDAC3HDAC4
SCHEMBL29263701 0.82 HDAC1 (0.72) TRPV1HDAC2HDAC1HDAC8HDAC3
SCHEMBL4938894 0.81 ACHE (0.57) ACHESGMS1SGMS2DPP4
SCHEMBL13903056 0.80 ALDH1A1 (0.58) ALOX5
SCHEMBL31390626 0.79 ACHE (0.60) ACHESGMS1SGMS2DPP4
SCHEMBL5724132 0.79 ACHE (0.60) ACHESGMS1SGMS2DPP4
SCHEMBL13903351 0.79 ALB (0.49) TRPV1HDAC2HDAC1HDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648612-B1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS LTD (JP) 1998-06-10 EP disclosed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US disclosed
EP-0648612-A1 Reversible heat-sensitive recording material MITSUBISHI PAPER MILLS, LTD. (JP) 1995-04-19 EP disclosed