Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2007721 | 0.87 | TNNC1 (0.48) | CYP4F2CYP4A11 | |
| SCHEMBL2007720 | 0.87 | TNNC1 (0.48) | CYP4F2CYP4A11 | |
| SCHEMBL15182005 | 0.86 | CYP4F2 (0.47) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29239895 | 0.86 | HDAC4 (0.42) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27875964 | 0.84 | CYP4F2 (0.46) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27776481 | 0.83 | CYP4F2 (0.44) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27776423 | 0.81 | CYP4F2 (0.38) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL289616 | 0.81 | PPARG (0.47) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL289617 | 0.81 | PPARG (0.47) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8436279 | 0.80 | CYP4F2 (0.43) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346495-A1 | METHODS AND COMPOSITIONS COMPRISING AN NFKB INHIBITOR AND AN ADJUVANT | THE UNIVERSITY OF CHICAGO (US) | 2021-11-11 | — | — | US | disclosed |
| US-9453226-B2 | Protection of cells from Alu-RNA-induced degeneration and inhibitors for protecting cells | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2016-09-27 | — | — | US | disclosed |
| US-20060024691-A1 | Novel pathways in the etiology of cancer | BUCK INSTITUTE FOR AGE RESEARCH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346495-A1 | METHODS AND COMPOSITIONS COMPRISING AN NFKB INHIBITOR AND AN ADJUVANT | NFKBIA, IKBKG, NFKB2 | CYP4F2 4658/4885CYP4A11 3265/4885KDM4E 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.