Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555777 | 0.81 | NOTUM (0.36) | NOTUMKDM4ENPC1MAPTRAB9A | |
| SCHEMBL3556715 | 0.79 | ALDH1A1 (0.40) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL3558793 | 0.78 | CREBBP (0.33) | NPC1RAB9ACREBBPBAZ2B | |
| SCHEMBL3558936 | 0.76 | KMT2A (0.47) | NPC1RAB9AMEN1KMT2ANPSR1 | |
| SCHEMBL3554094 | 0.74 | KMT2A (0.42) | NOTUMKDM4ENPC1MAPTRAB9A | |
| SCHEMBL1271943 | 0.74 | PDGFRA (0.41) | NOTUMMAPTCYP1A2LMNAHPGD | |
| SCHEMBL2475378 | 0.74 | NOTUM (0.45) | NOTUMKDM4ENPC1MAPTRAB9A | |
| SCHEMBL28598442 | 0.73 | PTGDR2 (0.41) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL23360886 | 0.70 | NOTUM (0.49) | NOTUMKDM4EMAPTHSP90AA1SLC22A12 | |
| SCHEMBL3282414 | 0.70 | NOTUM (0.41) | NOTUMKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094031-A1 | Alpha-L-arabinofuranosidase histochemical reporter gene assay | STOWERS INSTITUTE FOR MEDICAL RESEARCH | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094031-A1 | Alpha-L-arabinofuranosidase histochemical reporter gene assay | GUSB, FUCA1, ENGASE | NOTUM 291/4885KDM4E 3314/4885NPC1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.