Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475378 | 0.87 | NOTUM (0.45) | KMT2AMEN1KDM4ENPC1MAPT | |
| SCHEMBL27636554 | 0.83 | KMO (0.38) | NPSR1GAAKMOKCNH2 | |
| SCHEMBL28683409 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1KDM4ENPC1MAPT | |
| SCHEMBL28696581 | 0.80 | IDO1 (0.37) | KMT2AMEN1KDM4EATMNOTUM | |
| SCHEMBL3241798 | 0.78 | ABCB11 (0.46) | KMT2AMEN1KDM4ENPC1MAPT | |
| SCHEMBL28693273 | 0.78 | MTNR1A (0.49) | KDM4ENPC1MAPTRAB9ANOTUM | |
| SCHEMBL28977346 | 0.77 | AKR1C3 (0.49) | KMO | |
| SCHEMBL28706030 | 0.76 | BRD4 (0.45) | KDM4EMAPT | |
| SCHEMBL1333179 | 0.75 | HTT (0.54) | KMT2AMEN1KDM4ENPC1MAPT | |
| SCHEMBL9300394 | 0.75 | MEN1 (0.39) | KMT2AMEN1KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057625-B | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2023-11-24 | — | — | CN | disclosed |
| CN-114057625-A | C2-acyloxy-3-indolinone derivative and preparation method and application thereof | 五邑大学 | 2022-02-18 | — | — | CN | disclosed |
| EP-1567492-B1 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2013-05-22 | — | — | EP | disclosed |
| US-7718690-B2 | N-arylsulfonyl-3-aminoalkoxyindoles | RAMAKRISHNA VENKATA SATYA NIROGI | 2010-05-18 | — | — | US | disclosed |
| US-20090131507-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2009-05-21 | — | — | US | disclosed |
| EP-1567492-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | Suven Life Sciences Limited (IN) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004048328-A2 | N-ARYLSULFONYL-3-AMINOALKOXYINDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |
| US-6699685-B1 | (4),6,(7)-(DI,TRI)CHLOROINDOLYL-BETA-D-GALACTOSIDE INDICATORS; PRODUCE MAUVE OR MAGENTA PRECIPITATES WHEN REACTED UPON BY BETA-GALACTOSIDASE; CONTRASTS IN COLOR WITH GLUCURONIDASE SUBSTRATES | RCR SCIENTIFIC, INC. | 2004-03-02 | — | — | US | disclosed |
| US-5393662-A | Nutrient base medium containing chromogenic indolyl beta-galactosidase substrate forming insoluble colored compound upon reacting with beta-galactosidase | RCR SCIENTIFIC, INC. (US) | 1995-02-28 | — | — | US | disclosed |
| US-5364767-A | 6-chloroindole derivatives; colorimetric and quantitative analysis | RESEARCH ORGANICS, IN. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5358854-A | 6-chloroindolyl-beta-D-galactosie; 6-chloroindolyl-beta-D-gulcoronide 6-chloriindolyl-beta-D-gulcuronic acid monocyclohexylammonium salt | RESEARCH ORGANICS, INC. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5210022-A | Substrates sensitive to beta-galactosidase and beta-glucuronidase, quantitative analysis | RCR SCIENTIFIC, INC. (US) | 1993-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131507-A1 | N-arylsulfonyl-3-aminoalkoxyindoles | HTR3C, HTR3A, AANAT | KMT2A 1753/4885MEN1 1490/4885KDM4E 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.