Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29794124 | 1.00 | MAPK1 (0.68) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL3922528 | 0.84 | TDP1 (0.68) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| O-Xylene SCHEMBL27865799 | 0.82 | MAPK1 (0.76) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL58874 | 0.81 | MAPK1 (1.00) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL58809 | 0.81 | CYP3A4 (0.70) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL29376406 | 0.81 | MAPK1 (1.00) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL14926683 | 0.81 | HTR3E (0.53) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL62416 | 0.80 | HTR3E (0.46) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL2770967 | 0.79 | MAPK1 (0.73) | MAPK1TDP1CYP3A4TRPA1HTR3E | |
| SCHEMBL14926708 | 0.79 | HTR3E (0.52) | MAPK1TDP1CYP3A4TRPA1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350596-A | Polyurethane composite material, polyurethane and preparation method thereof | 万华化学集团股份有限公司 | 2025-01-24 | — | — | CN | claimed |
| CN-119186531-A | Chiral stationary phase derivatized by multi-functional hydroxypropyl-beta-cyclodextrin, preparation method and application thereof | 浙江工业大学 | 2024-12-27 | — | — | CN | claimed |
| CN-115960017-B | Modified acrylic ester monomer and photo-curable resin thereof | 上海华峰龙湾技术有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-117964892-A | Modified macromer, preparation method thereof and application thereof in polymer polyol | 中国石油化工股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116768764-A | Process for preparing urea derivatives | 安道麦阿甘有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116715830-A | Adduct type curing agent with adjustable xylene tolerance and preparation method thereof | 万华化学集团股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-116525948-A | Method for inhibiting corrosion of aluminum foil of lithium battery current collector based on isocyanate additive | 临沂大学 | 2023-08-01 | — | — | CN | claimed |
| CN-111471171-B | Arylsulfonic acid intermediate, preparation method thereof and application of aryl sulfonic acid intermediate in synthesizing low-temperature-sensitivity additive for concrete | 江苏苏博特新材料股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-115960017-A | Modified acrylate monomer and photocurable resin thereof | 上海华峰龙湾技术有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-111471172-B | Methyl aromatic ring polyether intermediate, preparation method thereof and application thereof in synthesizing small molecule concrete additive | 江苏苏博特新材料股份有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-111978448-A | Ureido-modified (S) -2-ethynylpyrrolidine and preparation method and application thereof | 北京大学 | 2020-11-24 | — | — | CN | claimed |
| CN-106892893-B | Method for preparing lactide from lactic acid oligomer | 中国科学院长春应用化学研究所 | 2020-09-25 | — | — | CN | claimed |
| CN-111471171-A | Aryl sulfonic acid intermediate, preparation method thereof and application thereof in synthesizing low-temperature-sensitivity additive for concrete | 江苏苏博特新材料股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-111471172-A | Methyl aromatic ring polyether intermediate, preparation method thereof and application thereof in synthesis of small molecule concrete additive | 江苏苏博特新材料股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-106751521-A | A kind of novel magnetic composite and preparation method thereof | 苏州缔绿电子科技有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-106008276-A | Synthesis method of phenylurea herbicide or deuteration-labeled phenylurea herbicide | 湖北出入境检验检疫局检验检疫技术中心 | 2016-10-12 | — | — | CN | claimed |
| US-20070249823-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-10-25 | — | — | US | claimed |
| WO-2007070804-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-06-21 | — | — | WO | claimed |
| EP-1754705-A2 | Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders | Genentech, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249823-A1 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | DPYD, PARP1, PARP2 | MAPK1 4251/4885TDP1 311/4885CYP3A4 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.