SCHEMBL6037451

SCHEMBL6037451

C=C(C)COC[Si](C)(C)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6037329 0.86 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL1806298 0.83 HSD17B10 (0.35) HSD17B10TDP1
SCHEMBL269320 0.80 HSD17B10 (0.30) HSD17B10TDP1
SCHEMBL7701977 0.77 HSD17B10 (0.31) HSD17B10TDP1
SCHEMBL332508 0.76
SCHEMBL8418941 0.74
SCHEMBL145162 0.74
SCHEMBL537647 0.74
SCHEMBL692373 0.74 CES2 (0.31)
SCHEMBL8377546 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2024-12-12 US claimed
EP-4448536-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2024-10-23 EP claimed
WO-2023113779-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2023-06-22 WO claimed
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2023-06-15 US claimed
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2024-12-12 US disclosed
EP-4448536-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2024-10-23 EP disclosed
CN-118401532-A High-purity polysiloxane macromer and preparation method thereof 盖列斯特有限公司 2024-07-26 CN disclosed
WO-2023113779-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2023-06-22 WO disclosed
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2023-06-15 US disclosed
US-20060222869-A1 Electropen lithography ENERGY, UNITED STATES DEPARTMENT 2006-10-05 US disclosed
US-5319051-A A hydrosiloxy or alkyenylsiloxy endcapped polysilane homo-or copolymer; chemical intermediates SHIN-ETSU CHEMICAL COMPANY, LIMITED (JP) 1994-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 HSD17B10 2634/4885TDP1 676/4885
US-20230183273-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 HSD17B10 2634/4885TDP1 676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.