SCHEMBL7701977

SCHEMBL7701977

C=C(C)COCC[Si](C)(C)Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692373 0.88 CES2 (0.31)
SCHEMBL7638458 0.87 HSD17B10 (0.31) HSD17B10TDP1
SCHEMBL8962563 0.86 CES2 (0.33)
SCHEMBL674775 0.84 HSD17B10 (0.32) HSD17B10TDP1
SCHEMBL23321700 0.84 CES2 (0.36)
SCHEMBL23321853 0.84 CES2 (0.36)
SCHEMBL23321608 0.84 CES2 (0.36)
SCHEMBL23322176 0.84 CES2 (0.36)
SCHEMBL23322074 0.84 CES2 (0.36)
SCHEMBL23322164 0.84 CES2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6344521-B1 LIVING POLYMERS FMC CORPORATION 2002-02-05 US disclosed
US-6271330-B1 POLYSILOXANES, TELECHELIC POLYMERS AND LIVING POLYMERS WITH FREE RADICAL CATALYST FMC CORPORATION 2001-08-07 US disclosed
US-6031060-A INCLUDES PROTECTED, FUNCTIONALIZED SILICONE POLYMERS, SUCH AS MONO-FUNCTIONAL, HOMOTELECHELIC, HETEROTELECHELIC, MACROMONOMER, AND RADIAL POLYMERS FMC CORPORATION (US) 2000-02-29 US disclosed
US-6020430-A LIVING POLYMERS FMC CORPORATION (US) 2000-02-01 US disclosed
US-5554706-A LOW TEMPERATURE LIQUID CRYSTALS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-09-10 US disclosed
EP-0695770-A1 COPOLYMER HAVING LIQUID CRYSTAL GROUP IN THE SIDE CHAIN SAGAMI CHEMICAL RESEARCH CENTER (JP) 1996-02-07 EP disclosed