Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TGM2 | P21980 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034875 | 0.82 | TGM2 (0.56) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6033928 | 0.79 | TGM2 (0.59) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034870 | 0.79 | TGM2 (0.60) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034127 | 0.78 | TGM2 (0.58) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034224 | 0.77 | TGM2 (0.59) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034377 | 0.77 | TGM2 (0.50) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034382 | 0.77 | TGM2 (0.59) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034917 | 0.77 | TGM2 (0.59) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6033990 | 0.77 | TGM2 (0.61) | MAPTGAAALDH1A1HSD17B10MAPK1 | |
| SCHEMBL6034346 | 0.77 | MAPK1 (0.63) | MAPTGAAALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183759-A1 | Tissue transglutaminase inhibitors | BRIGHAM AND WOMEN'S HOSPITAL, INC., THE | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183759-A1 | Tissue transglutaminase inhibitors | TGM2, HNMT, TPMT | MAPT 40/4885GAA 42/4885ALDH1A1 3116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.