Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.34 |
| ▸ | CPB1 | P15086 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10670324 | 0.78 | HRH4 (0.55) | HRH4HRH3ALDH1A1MEN1GLA | |
| SCHEMBL867807 | 0.78 | HRH4 (0.55) | HRH4HRH3ALDH1A1MEN1GLA | |
| SCHEMBL14025146 | 0.77 | CPB2 (0.40) | HRH4HRH3ALDH1A1MEN1GLA | |
| SCHEMBL14798187 | 0.77 | CYP1A2 (0.45) | ALDH1A1MEN1KMT2ACYP1A2NFKB1 | |
| SCHEMBL60911 | 0.77 | CYP1A2 (0.45) | ALDH1A1MEN1KMT2ACYP1A2NFKB1 | |
| Hydrochloric Acid SCHEMBL6697015 | 0.75 | TYR (0.45) | ALDH1A1MEN1KMT2ACYP1A2NFKB1 | |
| SCHEMBL594580 | 0.75 | CPB2 (0.42) | CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL11418503 | 0.74 | CPB2 (0.41) | CPB2CPB1 | |
| Hydrochloric Acid SCHEMBL1521823 | 0.74 | CPB2 (0.41) | CPB2CPB1 | |
| SCHEMBL1779971 | 0.72 | CPB2 (0.40) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9228004-B2 | Selection of host cells expressing protein at high levels | CHROMAGENICS B.V. (NL) | 2016-01-05 | — | — | US | disclosed |
| US-20140106401-A1 | SELECTION OF HOST CELLS EXPRESSING PROTEIN AT HIGH LEVELS | CHROMAGENICS B.V. (NL) | 2014-04-17 | — | — | US | disclosed |
| US-20060195935-A1 | Selection of host cells expressing protein at high levels | CHROMAGENICS B.V. (NL) | 2006-08-31 | — | — | US | disclosed |
| EP-0555315-B1 | HUMAN CELL LINE STABLY EXPRESSING 5cDNAs ENCODING PROCARCINOGEN-ACTIVATING ENZYMES | GENTEST CORP (US) | 2004-04-28 | — | — | EP | disclosed |
| US-5726041-A | Method for detecting a receptor-ligand complex using a cytochrome P450 reporter gene | GENTEST CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997008342-A1 | CYTOCHROME P450 REPORTER GENE | GENTEST CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |
| US-5429948-A | Human cell line stably expressing 5cDNAS encoding procarcinogen-activating enzymes and related mutagenicity assays | GENTEST CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0555315-A4 | HUMAN CELL LINE STABLY EXPRESSING 5CDNAS ENCODING PROCARCINOGEN-ACTIVATING ENZYMES | GENTEST CORP (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0555315-A1 | HUMAN CELL LINE STABLY EXPRESSING 5cDNAs ENCODING PROCARCINOGEN-ACTIVATING ENZYMES | GENTEST CORPORATION (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007085-A1 | HUMAN CELL LINE STABLY EXPRESSING 5cDNAs ENCODING PROCARCINOGEN-ACTIVATING ENZYMES | GENTEST CORPORATION (US) | 1992-04-30 | — | — | WO | disclosed |