SCHEMBL6037704

SCHEMBL6037704

COC1(OC)C=CC(C(CCC(O)C(=O)O)(c2ccccc2)c2ccccc2)=CC1

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 13/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28832854 0.77
SCHEMBL8135345 0.73 CHRM3 (0.35)
SCHEMBL27556498 0.71 KIF11 (0.34) KIF11
Methylene Chloride SCHEMBL27870524 0.71
SCHEMBL29175984 0.69 MAPT (0.36)
SCHEMBL29249882 0.67 ADORA2A (0.45)
SCHEMBL28304175 0.67 CHRM2 (0.31)
SCHEMBL5859589 0.60 KIF11 (0.43) KIF11
SCHEMBL2898260 0.60 KIF11 (0.60) KIF11
SCHEMBL28676858 0.58 SIGMAR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060188873-A1 Method for detecting a target polynucleotide ABEL ANDREAS 2006-08-24 US disclosed
EP-1064406-B1 SOLUTION PHASE NUCLEIC ACID hybridisation SANDWICH ASSAY NOVARTIS AG (CH) 2004-08-04 EP disclosed
EP-0760944-B1 PROCESS FOR DETECTING EVANESCENTLY EXCITED LUMINESCENCE NOVARTIS AG (CH) 2002-04-17 EP disclosed
US-5959292-A Process for detecting evanescently excited luminescence NOVARTIS CORPORATION (US) 1999-09-28 US disclosed
EP-0760944-A1 PROCESS FOR DETECTING EVANESCENTLY EXCITED LUMINESCENCE Novartis AG (CH) 1997-03-12 EP disclosed
WO-1995033197-A1 PROCESS FOR DETECTING EVANESCENTLY EXCITED LUMINESCENCE CIBA-GEIGY AG (CH) 1995-12-07 WO disclosed