Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CPA3 | P15088 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037833 | 1.00 | NPSR1 (0.49) | NPSR1CPA3MAPTRXFP1FOLH1 | |
| SCHEMBL7607301 | 0.95 | CPA3 (0.47) | NPSR1CPA3MAPTRXFP1FOLH1 | |
| SCHEMBL5053110 | 0.88 | FOLH1 (0.53) | FOLH1 | |
| SCHEMBL5059943 | 0.88 | FOLH1 (0.53) | FOLH1 | |
| SCHEMBL5054569 | 0.88 | FOLH1 (0.53) | FOLH1 | |
| SCHEMBL5053188 | 0.86 | FOLH1 (0.54) | FOLH1 | |
| SCHEMBL6037839 | 0.85 | CPA3 (0.58) | CPA3FOLH1 | |
| SCHEMBL7604478 | 0.83 | FOLH1 (0.52) | FOLH1 | |
| SCHEMBL6037767 | 0.83 | FOLH1 (0.46) | FOLH1 | |
| SCHEMBL5051342 | 0.82 | FOLH1 (0.59) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093991-A1 | COMPOUNDS WHICH BIND PSMA AND USES THEREOF | THE CLEVELAND CLINIC FOUNDATION (US) | 2006-09-08 | — | — | WO | disclosed |