Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.54 |
| ▸ | SPR | P35270 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038140 | 0.94 | HTR2A (0.60) | HTR2ABCHEACHEMAPTHDAC3 | |
| SCHEMBL6038156 | 0.92 | SPR (0.58) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5285108 | 0.91 | HTR2A (0.55) | HTR2ABCHEACHEMAPTHDAC3 | |
| SCHEMBL5285115 | 0.90 | HTR2A (0.54) | HTR2ABCHEACHEMAPTHDAC3 | |
| SCHEMBL6038221 | 0.90 | HDAC3 (0.60) | HTR2AMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL6038097 | 0.87 | KMT2A (0.54) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5280299 | 0.86 | HTR2A (0.49) | HTR2ABCHEACHEMAPTHDAC3 | |
| SCHEMBL6038106 | 0.86 | SPR (0.54) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6038113 | 0.85 | ACHE (0.51) | HTR2ABCHEACHEMAPTMTNR1A | |
| SCHEMBL6038137 | 0.82 | ACHE (0.48) | HTR2ABCHEACHEMAPTMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | HTR2A 2987/4885BCHE 1641/4885ACHE 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.