Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038041 | 0.85 | CCR3 (0.60) | CCR3MEN1KMT2A | |
| SCHEMBL6038203 | 0.75 | GAA (0.48) | MEN1KMT2A | |
| SCHEMBL5278692 | 0.75 | HRH2 (0.53) | CCR3MEN1KMT2A | |
| SCHEMBL5285712 | 0.74 | MEN1 (0.51) | CCR3MEN1KMT2A | |
| SCHEMBL6038000 | 0.74 | NAMPT (0.41) | MEN1KMT2A | |
| SCHEMBL6037892 | 0.74 | NAMPT (0.57) | — | |
| SCHEMBL6038031 | 0.74 | HTR2A (0.47) | MEN1KMT2A | |
| SCHEMBL6038332 | 0.73 | POLB (0.50) | — | |
| SCHEMBL6037966 | 0.73 | NAMPT (0.52) | — | |
| SCHEMBL5281631 | 0.73 | CHRM4 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | CCR3 3790/4885MEN1 2348/4885KMT2A 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.