Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038332 | 0.81 | POLB (0.50) | GAALMNAHTTTP53ALDH1A1 | |
| SCHEMBL6038000 | 0.77 | NAMPT (0.41) | GAALMNAHTTMEN1KMT2A | |
| SCHEMBL5277762 | 0.76 | GAA (0.48) | GAALMNAL3MBTL1HTTTP53 | |
| SCHEMBL6037892 | 0.75 | NAMPT (0.57) | POLB | |
| SCHEMBL6038135 | 0.75 | CCR3 (0.56) | MEN1KMT2A | |
| SCHEMBL5278888 | 0.74 | GAA (0.56) | GAALMNAHTTTP53MEN1 | |
| SCHEMBL5280748 | 0.74 | ALDH1A1 (0.50) | GAALMNAHTTTP53MEN1 | |
| SCHEMBL6038031 | 0.73 | HTR2A (0.47) | LMNAMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL6037966 | 0.72 | NAMPT (0.52) | POLB | |
| SCHEMBL6038104 | 0.72 | NAMPT (0.45) | RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | GAA 569/4885LMNA 851/4885L3MBTL1 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.