Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5283344 | 0.84 | HDAC3 (0.53) | CHRM4 | |
| SCHEMBL5291871 | 0.83 | FAAH (0.51) | CHRM4 | |
| SCHEMBL5324907 | 0.83 | BCHE (0.63) | CHRM4ACHEBCHE | |
| SCHEMBL5278692 | 0.81 | HRH2 (0.53) | CHRM4 | |
| SCHEMBL18826039 | 0.81 | CHRM4 (1.00) | CHRM4ACHE | |
| SCHEMBL7310558 | 0.80 | DRD2 (0.67) | — | |
| SCHEMBL5285712 | 0.80 | MEN1 (0.51) | CHRM4 | |
| SCHEMBL5282980 | 0.79 | CHRM4 (0.42) | CHRM4 | |
| SCHEMBL5278655 | 0.79 | BCHE (0.59) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL5285785 | 0.78 | CHRM4 (0.41) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | CHRM4 3413/4885ACHE 3161/4885BCHE 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.