Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286235 | 0.82 | HDAC1 (0.53) | GAAKDM4ENAMPTHDAC2HDAC8 | |
| SCHEMBL5284053 | 0.81 | NAMPT (0.49) | GAAKDM4ENAMPTLMNAPOLB | |
| SCHEMBL6037974 | 0.80 | LMNA (0.59) | GAAKDM4EEPHX2LMNAPOLB | |
| SCHEMBL13915578 | 0.78 | SPR (0.60) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL5281044 | 0.77 | GRIN2B (0.53) | — | |
| SCHEMBL6037885 | 0.77 | LMNA (0.55) | GAAKDM4EEPHX2LMNAPOLB | |
| SCHEMBL5281557 | 0.76 | LMNA (0.50) | GAAEPHX2LMNAKMT2AALDH1A1 | |
| SCHEMBL16610103 | 0.76 | CYP3A4 (0.61) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL17117361 | 0.76 | ESR1 (0.56) | ALDH1A1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL5280853 | 0.76 | LMNA (0.68) | GAAKDM4EEPHX2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | GAA 569/4885KDM4E 67/4885EPHX2 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.