Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19945995 | 0.83 | SMN1; SMN2 (0.36) | SMN1; SMN2ALOX15LMNA | |
| SCHEMBL57952 | 0.62 | NPSR1 (0.49) | SMN1; SMN2ALOX15LMNA | |
| SCHEMBL1816299 | 0.61 | SMN1; SMN2 (0.33) | SMN1; SMN2ALOX15TSHRLMNA | |
| SCHEMBL83640 | 0.59 | ALOX15 (0.52) | SMN1; SMN2ALOX15TSHRLMNA | |
| SCHEMBL21599089 | 0.59 | SMN1; SMN2 (0.33) | SMN1; SMN2ALOX15TSHRLMNA | |
| SCHEMBL28830577 | 0.58 | MAPT (0.43) | ALOX15TSHR | |
| SCHEMBL29421945 | 0.58 | CA2 (0.52) | ALOX15TSHR | |
| SCHEMBL6474982 | 0.58 | TSHR (0.39) | SMN1; SMN2ALOX15TSHRLMNA | |
| SCHEMBL8003558 | 0.57 | CA2 (0.46) | ALOX15TSHRLMNA | |
| SCHEMBL24158115 | 0.57 | SMN1; SMN2 (0.32) | SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141248-B2 | Methods of producing intraocular lenses | AMO GRONINGEN BV (NL) | 2006-11-28 | — | — | US | disclosed |
| CN-1201824-C | Aqueous solution for producing crystalline lens and material suitable for producing same | PHRMACIA & UPJOHN GRONINGEN B (NL) | 2005-05-18 | — | — | CN | disclosed |
| US-6861065-B2 | Method of producing intraocular lenses in vivo | ADVANCED MEDICAL OPTICS, INC. (US) | 2005-03-01 | — | — | US | disclosed |
| EP-1250162-B1 | MATERIALS SUITABLE FOR INTRAOCULAR LENS PRODUCTION | PHARMACIA GRONINGEN BV (NL) | 2004-09-15 | — | — | EP | disclosed |
| US-20040037867-A1 | Methods of producing intraocular lenses | ADVANCED MEDICAL OPTICS, INC. | 2004-02-26 | — | — | US | disclosed |
| US-20030208268-A1 | Method of producing intraocular lenses in vivo | ADVANCED MEDICAL OPTICS, INC. | 2003-11-06 | — | — | US | disclosed |
| US-6589550-B1 | Methods of producing intraocular lenses and materials suitable for their production | PHARMACIA GRONINGEN BV (NL) | 2003-07-08 | — | — | US | disclosed |
| CN-1293578-A | Method and materials for producing intracular lenses | PHRMACIA & UPJOHN GRONINGEN B (NL) | 2001-05-02 | — | — | CN | disclosed |