Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 9/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.53 |
| ▸ | CA12 | O43570 | 7/20 | 0.53 |
| ▸ | CA9 | Q16790 | 7/20 | 0.53 |
| ▸ | MMP2 | P08253 | 5/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202571 | 0.93 | MMP2 (0.53) | ALDH1A1TSHRHDAC1HDAC2CA1 | |
| SCHEMBL569559 | 0.88 | CA1 (0.65) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL569562 | 0.87 | CA12 (0.65) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL569947 | 0.87 | CA12 (0.65) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL5094941 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL14831226 | 0.84 | USP2 (0.56) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL24762017 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL29764347 | 0.84 | CA1 (0.56) | ALDH1A1TSHRCA1CA2CA12 | |
| SCHEMBL29262772 | 0.83 | CA12 (0.59) | ALDH1A1TSHRCA1CA2CA12 | |
| Dimethylamine SCHEMBL7701793 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TSHRHDAC1HDAC2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | ALDH1A1 781/4885TSHR 2191/4885HDAC1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.