Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038934 | 0.95 | FGFR1 (0.46) | FGFR1 | |
| SCHEMBL13999514 | 0.91 | FGFR1 (0.45) | FGFR1 | |
| SCHEMBL13999517 | 0.90 | FGFR1 (0.44) | FGFR1 | |
| SCHEMBL5107850 | 0.89 | FGFR1 (0.46) | FGFR1 | |
| SCHEMBL6038586 | 0.86 | BRAF (0.41) | FGFR1 | |
| SCHEMBL13999521 | 0.86 | FGFR1 (0.45) | FGFR1 | |
| SCHEMBL13999444 | 0.86 | KDR (0.43) | FGFR1 | |
| SCHEMBL6038469 | 0.85 | KDR (0.40) | FGFR1 | |
| SCHEMBL5114000 | 0.81 | ASAH1 (0.37) | FGFR1 | |
| SCHEMBL5107817 | 0.81 | FGFR1 (0.46) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1522540-A1 | AZAARENE DERIVATIVES | Eisai Co., Ltd. (JP) | 2005-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | FGFR1 595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.