Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13999518 | 0.91 | FGFR1 (0.40) | KDRBRAFKCNH2FGFR1GCK | |
| SCHEMBL6038934 | 0.87 | FGFR1 (0.46) | FGFR1 | |
| SCHEMBL6038393 | 0.85 | FGFR1 (0.46) | FGFR1 | |
| SCHEMBL6038586 | 0.84 | BRAF (0.41) | KDRBRAFFGFR1S1PR1 | |
| SCHEMBL5115194 | 0.82 | S1PR1 (0.36) | KDRBRAFKCNH2S1PR1 | |
| SCHEMBL5107877 | 0.81 | S1PR1 (0.35) | KDRBRAFKCNH2S1PR1 | |
| SCHEMBL6038635 | 0.81 | KDR (0.36) | KDRKCNH2S1PR1 | |
| SCHEMBL6038632 | 0.80 | S1PR1 (0.35) | KDRBRAFKCNH2S1PR1 | |
| SCHEMBL13999521 | 0.78 | FGFR1 (0.45) | FGFR1 | |
| SCHEMBL5107817 | 0.78 | FGFR1 (0.46) | KDRBRAFFGFR1GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1522540-A1 | AZAARENE DERIVATIVES | Eisai Co., Ltd. (JP) | 2005-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004029-A1 | Nitrogen-containing aromatic derivatives | NR0B2, NR0B1, NR4A1 | KDR 1940/4885BRAF 1488/4885KCNH2 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.