Spermidine

Spermidine

SCHEMBL6038403

NCCCCNCCCN.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.58
F13A1 P00488 2/20 0.58
CA2 P00918 2/20 0.58
CYP1A2 P05177 2/20 0.58
ALOX15 P16050 2/20 0.58
CA4 P22748 2/20 0.58
CA6 P23280 2/20 0.58
CA5A P35218 2/20 0.58
THPO P40225 2/20 0.58
CA7 P43166 2/20 0.58
CA9 Q16790 2/20 0.58
CA14 Q9ULX7 2/20 0.58
CA5B Q9Y2D0 2/20 0.58
CA1 P00915 1/20 0.58
CA3 P07451 1/20 0.58
CYP2C9 P11712 1/20 0.58
PKM P14618 1/20 0.58
TSHR P16473 1/20 0.58
MTOR P42345 1/20 0.58
LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spermine SCHEMBL867750 0.98 CA12 (0.56) CA12F13A1CA2CYP1A2ALOX15
Spermidine SCHEMBL867617 0.87 CA12 (0.70) CA12F13A1CA2CYP1A2ALOX15
Spermidine SCHEMBL28472688 0.85 CA12 (0.67) CA12F13A1CA2CYP1A2ALOX15
Pyrophosphoric Acid SCHEMBL11234659 0.85 CA12 (0.52) CA12F13A1CA2CYP1A2ALOX15
Spermidine SCHEMBL343200 0.85 CA12 (0.67) CA12F13A1CA2CYP1A2ALOX15
Spermine SCHEMBL2058654 0.84 CA12 (0.68) CA12F13A1CA2CYP1A2ALOX15
Spermine SCHEMBL867751 0.84 CA12 (0.68) CA12F13A1CA2CYP1A2ALOX15
Pyrophosphoric Acid SCHEMBL17311822 0.84 FDPS (0.59) CA12CA2CYP1A2CA4CA6
Spermine SCHEMBL364155 0.82 CA12 (0.65) CA12F13A1CA2CYP1A2ALOX15
Phosphoric Acid SCHEMBL15512587 0.82 CA12 (0.62) CA12F13A1CA2CYP1A2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060228813-A1 Method for immobilizing biomolecules on metal oxide substrates WU YING 2006-10-12 US disclosed
EP-1622714-A1 METHOD FOR IMMOBILIZING BIOMOLECULES ON METAL OXIDE SUBSTRATES PamGene B.V. (NL) 2006-02-08 EP disclosed
WO-2004089531-A1 METHOD FOR IMMOBILIZING BIOMOLECULES ON METAL OXIDE SUBSTRATES PAMGENE B.V. (NL) 2004-10-21 WO disclosed