SCHEMBL60385

SCHEMBL60385

CN(C)c1ccc(C#N)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.58
TSHR P16473 4/20 0.58
ALOX15 P16050 2/20 0.58
HSD17B10 Q99714 1/20 0.58
CYP2A6 P11509 2/20 0.52
MAPT P10636 2/20 0.52
APP P05067 2/20 0.49
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7262864 0.93 APP (0.53) ALDH1A1TSHRALOX15HSD17B10CYP2A6
SCHEMBL8849587 0.93 ALDH1A1 (0.50) ALDH1A1TSHRALOX15HSD17B10CYP2A6
SCHEMBL10630522 0.89 ALDH1A1 (0.46) ALDH1A1TSHRALOX15HSD17B10CYP2A6
SCHEMBL27807876 0.88 TSHR (0.56) ALDH1A1TSHRALOX15HSD17B10CYP2A6
SCHEMBL22995534 0.87 KDM1A (0.53) ALDH1A1TSHRALOX15HSD17B10CYP2A6
SCHEMBL31958 0.87 SLC6A4 (0.49) ALDH1A1TSHRALOX15HSD17B10CYP2A6
SCHEMBL8661516 0.87 ALDH1A1 (0.59) ALDH1A1TSHRALOX15HSD17B10MAPT
SCHEMBL1092248 0.87 KDM4E (0.63) ALDH1A1ALOX15CYP2A6MAPTAPP
SCHEMBL1092250 0.87 KDM4E (0.63) ALDH1A1ALOX15CYP2A6MAPTAPP
SCHEMBL12230429 0.85 ALDH1A1 (0.42) ALDH1A1TSHRALOX15HSD17B10CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1683 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4479101-B1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUE COHESIVES (FR) 2026-03-04 EP claimed
EP-4661925-A1 COATED CATHETER AND METHOD OF COATING Bard Access Systems, Inc. (US) 2025-12-17 EP claimed
EP-4582402-A1 SLIP Karlsruher Institut für Technologie (DE) 2025-07-09 EP claimed
US-12329877-B2 Surgical glues based on monomers comprising a phosphate function UNIVERSITE DE HAUTE ALSACE (FR) 2025-06-17 US claimed
US-20250152772-A1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUES COHESIVES (FR) 2025-05-15 US claimed
EP-4479101-A1 PHOTOPOLYMERISABLE COMPOSITION FOR ADHESIVE FOR BIOLOGICAL TISSUE Cohesives (FR) 2024-12-25 EP claimed
CN-118834161-A Preparation method of 3-sulfonyl-5-acetyl-1, 4 dihydropyridine compound 西北工业大学 2024-10-25 CN claimed
WO-2024191858-A1 COATED CATHETER AND METHOD OF COATING BARD ACCESS SYSTEMS, INC. (US) 2024-09-19 WO claimed
US-20240299630-A1 Coated Medical Devices and Methods of Coating BARD ACCESS SYSTEMS, INC. 2024-09-12 US claimed
CN-118615492-A Coated medical device and coating method 巴德阿克塞斯系统股份有限公司 2024-09-10 CN claimed
WO-1995030890-A1 FLUORESCENCE METHOD FOR DETERMINING PROPERTIES OF A POLYMER COATING OR FILM SPECTRA GROUP LIMITED, INC. (US) 1995-11-16 WO claimed
US-4900859-A Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde HOFFMAN-LA ROCHE INC. (US) 1990-02-13 US claimed
EP-0136186-B1 PHOTOCURABLE RESIN COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-09-06 EP claimed
EP-0318826-A2 Process for the preparation of 4-dimethylamino-3,5-dimethoxybenzaldehyde F. HOFFMANN-LA ROCHE AG (CH) 1989-06-07 EP claimed
EP-0130117-B1 LUMINESCENT MATERIAL HAVING A SOLID MATRIX WITH A LUMINESCENT COMPOUND DISTRIBUTED INSIDE, PROCESS FOR ITS MANUFACTURE AND ITS USE IN A PHOTOPILE CNRS, Centre National de la Recherche Scientifique (FR) 1987-04-15 EP claimed
US-4647400-A Luminescent material or phosphor having a solid matrix within which is distributed a fluorescent compound, its preparation process and its use in a photovoltaic cell CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1987-03-03 US claimed
US-4548689-A RADICAL POLYMERIZABLE MONOMER, KETOCARBONYL COMPOUND AND MERCAPTOB MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-10-22 US claimed
EP-0130117-A1 Luminescent material having a solid matrix with a luminescent compound distributed inside, process for its manufacture and its use in a photopile CNRS, Centre National de la Recherche Scientifique (FR) 1985-01-02 EP claimed
US-4076646-A O- OR M-TERPHENYLS HITACHI, LTD. (JA) 1978-02-28 US claimed
US-4011173-A MODIFIED NEMATIC MIXTURES WITH POSITIVE DIELECTRIC ANISOTROPY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-03-08 US claimed