Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | IL18 | Q14116 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60385 | 0.87 | ALDH1A1 (0.58) | MAPTKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL8551347 | 0.87 | SLC6A4 (0.45) | SLC6A4PARP15PARP10PARP2MAPT | |
| SCHEMBL7041250 | 0.82 | PARP15 (0.63) | SLC6A4PARP15PARP10PARP2MAPT | |
| SCHEMBL8852392 | 0.82 | PARP15 (0.63) | SLC6A4PARP15PARP10PARP2MAPT | |
| SCHEMBL13018337 | 0.82 | ALDH1A1 (0.65) | MAPTKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL13018335 | 0.82 | ALDH1A1 (0.65) | MAPTKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL3946527 | 0.82 | ALDH1A1 (0.65) | MAPTKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL8849587 | 0.81 | ALDH1A1 (0.50) | MAPTKDM4EMEN1LMNAMAPK1 | |
| SCHEMBL7262864 | 0.81 | APP (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL31122257 | 0.80 | SLC6A4 (0.40) | SLC6A4PARP15PARP10PARP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |